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    9.1

    9.1

    Minnesota Code 9-1: low QRS voltage — pericardial effusion, lung disease, amyloidosis and other causes.

    Code 9.1 — Minnesota Code 9-1: low QRS amplitude (low voltage). The QRS complexes are unusually small: the peak-to-peak amplitude is 5 mm or less in all limb leads, or 10 mm or less in all precordial leads. Low voltage means that either the heart produces weaker electrical forces, or something between the heart and the electrodes (fluid, air, fat or abnormal tissue) attenuates them.

    Minnesota Code 9QRS voltageLow voltage
    Limb leadsQRS ≤ 5 mm in all
    Precordial leadsQRS ≤ 10 mm in all
    Measuredpeak to peak (R + S)
    Key testechocardiography
    Normal QRS amplitude compared with a low-voltage QRS complex of less than 5 millimetres Normal QRS ≈ 12 mm Code 9-1 QRS ≤ 5 mm
    Figure 1. Left: normal QRS amplitude in a limb lead. Right: low voltage — total QRS amplitude ≤ 5 mm (Minnesota 9-1), often with small P and T waves.

    Causes

    MechanismExamples
    Fluid or tissue around the heartPericardial effusion (with fast heart rate — risk of tamponade), pleural effusion, generalised oedema
    Air or distanceEmphysema/COPD, pneumothorax, obesity
    Heart muscle replaced or damagedCardiac amyloidosis (low voltage despite thick walls), extensive infarction, dilated cardiomyopathy, myocarditis
    MetabolicHypothyroidism (myxoedema)
    TechnicalIncorrect calibration (e.g. 5 mm/mV), electrode problems

    Clinical significance

    Low voltage is a non-specific but important finding, especially when it is new. A combination of low voltage with a fast heart rate and breathlessness may indicate a large pericardial effusion. Low voltage together with thick ventricular walls on echocardiography is a classic clue to cardiac amyloidosis. The first steps are to check calibration and to perform echocardiography.

    Seek emergency care

    if low voltage is found together with breathlessness, chest pain, fast heart rate, low blood pressure or fainting.

    References

    1. Prineas RJ, Crow RS, Zhang ZM. The Minnesota Code Manual of Electrocardiographic Findings. 2nd ed. London: Springer; 2010. doi:10.1007/978-1-84882-778-3

    This article is for general information and does not replace a consultation with a doctor. ECG findings must be interpreted by a physician together with symptoms and other tests.

    Published on 14 May 2019